RT - Journal TY - JOUR A1 - Kumar, Piyush A1 - Mehta, Ankita T1 - Esophageal cancer: Treatment challenges and controversies YR - 2021/1/1 JF - Journal of Current Oncology JO - J Curr Oncol SP - 41 OP - 48 VO - 4 IS - 1 UL - http://www.https://journalofcurrentoncology.org//article.asp?issn=2589-8892;year=2021;volume=4;issue=1;spage=41;epage=48;aulast=Kumar;t=5 DO - 10.4103/jco.jco_13_21 N2 - The poor outcomes of esophageal malignancies in terms of local control and survival rates have perplexed radiation oncologists since long time. Chemoradiation has been recognized as a key definitive treatment modality with outcomes comparable to that of surgery. It offers a potential radical treatment option to patients unfit for surgery with the advantage of organ preservation. However, a clear consensus in terms of indications, dose schedules, and techniques of radiation is lacking. In pre- and post-operative settings, lower dose schedules of radiation are recommended. Some evidences suggest that patients receiving radical dose of radiation may derive survival benefit from increased doses. Low-quality emerging evidence suggests promising outcomes with brachytherapy but it needs to be testified further. A detailed review of the existing literature might help to address the controversies in clinical practice. ER -