Close
  Indian J Med Microbiol
 

Figure 3: Step 1: The shortened telomere after replication. Step 2: TERT recognizes the shortened telomere and adds complementary nucleotides using TERC. Step 3: The process is repeated many times till the length is restored to almost the original size. The lagging strand is also elongated using polymerase α and primase. The end repair problem, however, prevents flush ends at termini and creates a 3′-overhang

Figure 3: Step 1: The shortened telomere after replication. Step 2: TERT recognizes the shortened telomere and adds complementary nucleotides using TERC. Step 3: The process is repeated many times till the length is restored to almost the original size. The lagging strand is also elongated using polymerase α and primase. The end repair problem, however, prevents flush ends at termini and creates a 3′-overhang