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  Indian J Med Microbiol
 

Figure 3: Immunohistochemistry of mismatch repair (MMR) proteins. MMR-deficient tumor with loss of (A) MLH1 and (B) PMS2 nuclear expression in tumor cells. Note the intact nuclear expression in stromal cells and lymphocytes that acts as an internal control. MSH2 (C) and MSH6 (D) showed intact nuclear expression in tumor cells. MLH1 = MutL homolog 1, MSH2 = MutS homolog 2, MSH6 = MutS homolog 6, PMS2 = PMS1 Homolog 2

Figure 3: Immunohistochemistry of mismatch repair (MMR) proteins. MMR-deficient tumor with loss of (A) MLH1 and (B) PMS2 nuclear expression in tumor cells. Note the intact nuclear expression in stromal cells and lymphocytes that acts as an internal control. MSH2 (C) and MSH6 (D) showed intact nuclear expression in tumor cells. MLH1 = MutL homolog 1, MSH2 = MutS homolog 2, MSH6 = MutS homolog 6, PMS2 = PMS1 Homolog 2