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  Indian J Med Microbiol
 

Figure 4: Represents the immunological perspective of HPV. Innate and adaptive immune responses to HPV infection are moved away from effective TH1-like responses in genital verrucas and respiratory papillomas, causing HPV-induced disease. The adaptive immune response is polarized due to the failure of LCs to mature and then present peptides to T cells, which results in altered LC signaling that leads to a TH2 T-cell bias, when combined with the lack of NK activity

Figure 4: Represents the immunological perspective of HPV. Innate and adaptive immune responses to HPV infection are moved away from effective TH1-like responses in genital verrucas and respiratory papillomas, causing HPV-induced disease. The adaptive immune response is polarized due to the failure of LCs to mature and then present peptides to T cells, which results in altered LC signaling that leads to a TH2 T-cell bias, when combined with the lack of NK activity